Sardines contain very interesting matter, purines. Purines are found in plants, wire cloche animals and in humans. These are substances that some people may prove to be a major cause of some diseases and therefore excessive intake of these substances known to create problems. Metabolism of purines are broken down to the level ureične acid precipitates and creates damage to the kidneys and stimulates the formation of stones in the kidney wire cloche or bile. Therefore, though cautiously with sardines and foods that contain purines.
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